Botulinum Toxins (BOTOX, DYSPORT, MYOBLOC and XEOMIN) - 10/13
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چکیده
Botulinum is a family of toxins produced by the anaerobic organism Clostridia botulinum. There are seven distinct serotypes designated as type A, B, C-1, D, E, F, and G. In the United States, four preparations of botulinum are commercially available, three using type A serotype and one using type B. The three formulations of botulinum toxin type A are onabotulinumtoxinA (BOTOX), abobotulinumtoxinA (DYSPORT), and incobotulinumtoxinA (XEOMIN). RimabotulinumtoxinB contains botulinum toxin type B (MYOBLOC). When administered intramuscularly, all botulinum toxins reduce muscle tone by interfering with the release of acetylcholine from nerve endings.
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